Meredith : Okay, here it is, your choice... it's simple, her or me, and I'm sure she is really great. But Derek, I love you, in a really, really big pretend to like your taste in music, let you eat the last piece of cheesecake, hold a radio over my head outside your window, unfortunate way that makes me hate you, love you. So pick me, choose me, love me
Izzie : I am an optimist. I am a fool. I am not sure. Because I'm your best friend, because I love you, if what you want is to be with Callie then I will do everything in my power to support you and help you make your marriage work. But because I'm your best friend, because I love you, I also have to say.. that I'm in love with you. I'm in love with you. I can't promise a future, I can't promise perfection, because we're us, I'm me and you're you. No one knows what will happen. But in my heart, I am sure. I'm in love with you George.And I hope you're in love with me too. Say something.